Pamela Itkin-Ansari’s Research Report
“We are interested in identifying the master regulators of growth control in pancreatic ductal adenocarcinoma (PDA). We found that the transcriptional repressor Id3 is profoundly upregulated in human PDA.
We are now studying Id3 interacting genes in order to identify optimal targets for drug discovery efforts for PDA.” (SanfordBurnham.org)
Above : Id3 (green) is strikingly upregulated in murine pancreatic intraepithelial neoplasia (mucin, red) and in human pancreatic ductal adenocarcinoma (PDA)
Colourful cancer cells snag micro-photography prize.
An ovarian cancer researcher found the beauty in a horrific disease to win the 2011 IN Cell Analyzer Image Competition. Geoffrey Grandjean from the MD Anderson Cancer Center in Houston, Texas captured this image of human cancer cells to win the prize.
The cells’ kaleidoscope of colours come from stains that show DNA in red and microtubules in green. Images of this type help the researchers identify areas to attack in cancer therapies.
This image will be shown off with the other category winners on the big screen in New York’s Times Square on April 20-22. If you can’t make it to the Big Apple this spring, you can still check out all the winners in GE Healthcare’s online gallery.
Ovarian cancer cells have also been made to fluoresce to help doctors remove them more accurately.